multiple endocrine neoplasia type IIb

Multiple endocrine neoplasia (MEN) type IIb, also known as MEN type 3 (MEN3) or mucosal neuroma syndrome , accounts for only 5% cases of MEN2 and is characterized by:

• pheochromocytoma(s): in 50% of patients, often bilateral, and can be extra-adrenal
• medullary thyroid cancer: 100% of patients; aggressive, and may secrete calcitonin
• mucosal neuroma(s) / ganglioneuroma(s)
• marfanoid habitus

Mnemonic:

• PMMM

See also

• MEN1 (Wermer syndrome)
• MEN2 (multiple endocrine adenomatosis)
  • MEN2a (Sipple syndrome)
  • MEN2b (mucosal neuroma syndrome)
  • familial medullary thyroid carcinoma
• MEN4
• Carney complex

Siehe auch:

• Phäochromozytom
• benignes Ganglioneurom
• Medulläres Schilddrüsenkarzinom
• MEN IIa
• Multiple endokrine Neoplasie
• Multiple endokrine Neoplasien Typ 2
• marfanoid

und weiter:

• Marfan-Syndrom
• multiple endocrine neoplasia type IIa
• multiple endokrine Neoplasie Typ 1
• multiple endocrine neoplasia syndromes