Uterine enlargement (differential)

Uterine enlargement can occur in a number of situations from both diffuse and focal processes. These include:

gestation related events
- normal intrauterine pregnancy
- molar pregnancy - gestational trophoblastic disease
- postpartum uterus - still larger than usual
hormonal causes
- exogenous hormones
  - estroprogesterone (oral contraceptive pills)
  - tamoxifen
- endogenous hormones
myometrial tumorous lesions
- benign
  - uterine leiomyomas: common cause
    - large uterine leiomyoma
    - multiple leiomyomata
    - uterine leiomyomatosis
- malignant
  - uterine leiomyosarcoma
endometrial tumors lesions
- endometrial carcinoma
- endometrial stromal sarcoma
- malignant mixed Mullerian tumor of the uterus
other neoplastic conditions
- uterine lymphoma
- metastases to the uterus
adenomyosis: a common cause
- diffuse adenomyosis
- uterine adenomyoma
dilatation of the uterine cavity or contents within the uterine cavity - can occur for some reasons and can cause
vascular causes
- uterine arteriovenous malformations
- pelvic congestion syndrome