adult cystic renal disease
Adult cystic renal disease comprises multiple distinct hereditary and non-hereditary disease processes.
Pathology
Etiology
Hereditary
- adult polycystic kidney disease (APCKD), a.k.a. autosomal dominant polycystic kidney disease (ADPCKD)
- medullary cystic kidney disease
- von Hippel-Lindau disease
- tuberous sclerosis
Non-hereditary
- acquired renal cysts
- simple: extremely common, 50% of which occur in those over the age of 50, many causes including lithium nephropathy
- acquired cystic kidney disease: seen in ESRF
- medullary sponge kidney
- multicystic dysplastic kidney
- glomerulocystic disease
- localized renal cystic disease
- renal cell carcinoma: not a renal cystic disease but essential to remember as 10% of cases of renal cell carcinoma are primarily cystic
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