Eye of the tiger sign (globus pallidus)
The eye of the tiger sign refers to abnormal low T2 signal on MRI (due to abnormal accumulation of iron) in the globus pallidus with a longitudinal stripe of high signal (due to gliosis and spongiosis).
The eye of the tiger sign is most classically associated with pantothenate kinase-associated neurodegeneration although it is not pathognomonic . There are no formalized criteria for the sign and other conditions may demonstrate a similar appearance, such as Wilson disease , atypical parkinsonism and organophosphate poisoning ; it may also be a normal finding on a 3 T magnet . Therefore, caution should be used when interpreting this sign.
Siehe auch:
- Basalganglienverkalkungen
- T2 hyperintense Basalganglien
- Globus pallidus
- basal ganglia T1 hyperintensity
- Kortikobasale Degeneration
- decreased T2 signal in the basal ganglia
- Neurodegeneration mit Eisenablagerung im Gehirn
und weiter:
Assoziationen und Differentialdiagnosen zu eye of tiger sign: