eye of tiger sign

The eye of the tiger sign refers to abnormal low T2 signal on MRI (due to abnormal accumulation of iron) in the globus pallidus with a longitudinal stripe of high signal (due to gliosis and spongiosis).

The eye of the tiger sign is most classically associated with pantothenate kinase-associated neurodegeneration​ although it is not pathognomonic . There are no formalized criteria for the sign and other conditions may demonstrate a similar appearance, such as Wilson disease , atypical parkinsonism and organophosphate poisoning ; it may also be a normal finding on a 3 T magnet . Therefore, caution should be used when interpreting this sign.

Siehe auch:
und weiter: