Gardner syndrome

Pharyngeal

desmoid-type fibromatosis in a pediatric patient with Gardner"s syndrome. Axial CT image shows an oropharyngeal well circumscribed, soft tissue mass, with similar attenuation than the muscles, and slight enhancement after contrast administration. The airway is almost completely occupied by the mass.

www.eurorad.org • CC by-nc-sa-4.0

Pharyngeal

desmoid-type fibromatosis in a pediatric patient with Gardner"s syndrome. Coronal CT image depicts the same oropharyngeal soft tissue mass.

www.eurorad.org • CC by-nc-sa-4.0

Pharyngeal

desmoid-type fibromatosis in a pediatric patient with Gardner"s syndrome. On T2-weighted axial image the mass is heterogeneous, most of it hyperintense.

www.eurorad.org • CC by-nc-sa-4.0

Pharyngeal

desmoid-type fibromatosis in a pediatric patient with Gardner"s syndrome. T1-weighted sagittal after contrast administration image manifests a solid, well-circumscribed mass with a homogeneous enhancement.

www.eurorad.org • CC by-nc-sa-4.0

Radiological

review of skull lesions. Gardner Syndrome (multiple osteomas). Axial head CT images (a–c) show multiple osteomas in the ethmoid air cells (dashed arrows), left ramus of the mandible (arrowhead) and right anterior wall of the maxillary sinus (thin arrow). This patient was also found to have a mesenteric desmoid tumour (thick arrow, d)

insightsimaging.springeropen.com • Open Access

Osteoma •

Gardner syndrome - Ganzer Fall bei Radiopaedia

Ibrahim, D. Gardner syndrome. Case study, Radiopaedia.org. (accessed on 20 Oct 2022) https://doi.org/10.53347/rID-53473 • CC by-nc-sa 3.0 (modified)

Gardner

syndrome • Gardner syndrome - Ganzer Fall bei Radiopaedia

Gerstenmaier, J. Gardner syndrome. Case study, Radiopaedia.org. (accessed on 06 Nov 2022) https://doi.org/10.53347/rID-31382 • CC by-nc-sa 3.0 (modified)

Gardner

syndrome • Gardner syndrome - Ganzer Fall bei Radiopaedia

Knipe, H. Gardner syndrome. Case study, Radiopaedia.org. (accessed on 06 Nov 2022) https://doi.org/10.53347/rID-57976 • CC by-nc-sa 3.0 (modified)

Gardner

syndrome • Gardner syndrome - Ganzer Fall bei Radiopaedia

Samir, A. Gardner syndrome. Case study, Radiopaedia.org. (accessed on 06 Nov 2022) https://doi.org/10.53347/rID-72868 • CC by-nc-sa 3.0 (modified)

Radiopaedia • CC-by-nc-sa 3.0 • de

Gardner syndrome is one of the polyposis syndromes. It is characterized by:

familial adenopolyposis
multiple osteomas: especially of the mandible, skull, and long bones
epidermal cysts
fibromatoses
desmoid tumors of mesentery and anterior abdominal wall

Other abnormalities include:

Pathology

There is an autosomal dominant inheritance in the FAP gene (chromosome 5q) in a majority of patients but with 20% of cases resulting from new mutations. Extracolonic features often precede the diagnosis of colonic polyps.