Technetium 99m-methyl diphosphonate

Technetium 99m-methyl diphosphonate (99mTc MDP) is a radiotracer used in nuclear medicine especially for bone scintigraphy. Any disease process which results in extracellular fluid expansion will lead to accumulation of this tracer.

Radionuclide profile

• photon energy: 140 keV
• physical half life: 6 hours
• critical organ: bladder

Uses

• osteomyelitis
• fractures, including stress and insufficiency fractures
• malignancy, e.g. osteoid osteoma, bone metastases, soft tissue sarcomas
• painful scoliosis
• post-traumatic hematomas, myositis ossificans, heterotopic ossification
• tumoral calcinosis
• metastatic pulmonary calcification
• sickle cell disease