features of intracranial primary CNS lymphoma in immune competent patients. Axial post-contrast T1WI shows a slit-like center (white arrow) in an otherwise intensely, solidly contrast-enhancing mass in the right frontal white-matter. The mass causes little mass-effect relative to its large size.
features of intracranial primary CNS lymphoma in immune competent patients. Axial post-contrast T1WI shows a subcortical lesion with two deep indentations reflecting the overlying sulci (two overlapping crescents).
features of intracranial primary CNS lymphoma in immune competent patients. Axial T2WI, T1WI and contrast-enhanced T1WI as well as ADC and DWI maps show the classic appearance of PCNSL where the mass is isointense to mildly hypointense on T2WI and isointense on T1WI (relative to gray-matter) and shows predominantly solid, intense contrast enhancement (1a-1d). The mass is also in a typical distribution abutting a CSF-containing space (in the splenium of the corpus callosum abutting the lateral ventricles in this case). The mass is associated with extensive perilesional T2-hyperintensity. On ADC and DWI, the mass shows diffusion restriction.
features of intracranial primary CNS lymphoma in immune competent patients. Post-contrast T1WI in the axial, coronal and sagittal planes show two intensely, solidly contrast-enhancing masses (2a-2c). The larger one involves the hypothalamus and optic chiasm as well as the pituitary gland. The other one is subcortically located in the left temporal lobe.
features of intracranial primary CNS lymphoma in immune competent patients. Axial pre-contrast T1WI shows a hyperintense mass in the right temporal lobe.
features of intracranial primary CNS lymphoma in immune competent patients. Axial post-contrast T1WI and cerebral blood volume color map from perfusion exam show the reduced cerebral blood volume values in the tumor (6a-b).
imaging findings in AIDS-related diffuse large B cell lymphoma. Axial CT image (a) demonstrates bilateral axillary lymphadenopathy, proven to be DLBCL after biopsy. The patient successfully completed treatment but developed CNS symptoms 1 year later. MRI of the brain (b) showed a large heterogenous mass in the left cerebral hemisphere which biopsy was proven to be lymphoma. A previous MRI brain (c) was negative for CNS involvement
resonance imaging of sellar and juxtasellar abnormalities in the paediatric population: an imaging review. Leptomeningeal spread of lymphoma. Sagittal post contrast T1WI demonstrates diffuse intracranial and spinal leptomeningeal enhancement in a 22-month-old infant boy with lymphoma including the sella and parasellar subarachnoid space
CNS lymphoma refers to the involvement of the central nervous system with lymphoma. It can be broadly divided into primary and secondary, with a number of special types of also recognized.
- primary CNS lymphoma (PCNSL)
- secondary CNS lymphoma
Note that this is a simplified version of the current WHO classification of CNS tumors, which divides CNS lymphoma into a larger number of subtypes.
- verdickter Hypophysenstiel
- intraventrikuläres Meningeom
- Tuberkulose des ZNS
- Intracranial tuberculous granuloma
- zerebrale Kryptokokkose
- Tumefaktive Multiple Sklerose
- tumefaktive Demyelinisierung
- hypertrophe Pachymeningitis
- intrakranielle Tuberkulose
- boomerang sign
- pineal lymphoma
- intraventricular B cell lymphoma
- primary spinal lymphoma
- Burkitt-Lymphom des ZNS
- primary CNS lymphoma: involving the septum pellucidum
- Lymphom des spinalen Myelons