Hypertensive intracerebral hemorrhage

Hypertensive intracerebral hemorrhages are common. In fact, hypertension is the most common cause of intracerebral hemorrhages. They can be conveniently divided according to their typical locations which include, in order of frequency:

• basal ganglia hemorrhage (especially the putamen)
• thalamic hemorrhage
• pontine hemorrhage
• cerebellar hemorrhage

Clinical presentation

Patients will present depending on the region and size of the hemorrhage:

• basal ganglia hemorrhage usually presents with ipsilateral deviation of the eyes due to descending capsular pathways from the frontal eye field
• thalamic hemorrhage often presents with downward deviation of eyes and lack of pupillary response to light
• pontine hemorrhage usually causes coma due to disruption of the reticular activating system (unless small) and quadriparesis due to disruption of the corticospinal tract

Pathology

Long-standing poorly controlled hypertension leads to a variety of pathological changes in the vessels.

• microaneurysms of perforating arteries (Charcot-Bouchard aneurysms) 
  • small (0.3-0.9 mm) diameter 
  • occur on small (0.1-0.3 mm) diameter arteries
  • distribution which matches the incidence of hypertensive hemorrhages
    • 80% lenticulostriate
    • 10% pons
    • 10% cerebellum
  • found in hypertensive patients
  • may thrombose, leak (see cerebral microhemorrhages) or rupture
• accelerated atherosclerosis: affects larger vessels
• hyaline arteriosclerosis
• hyperplastic arteriosclerosis: seen in very elevated and protracted cases

Treatment and Prognosis 

Hemorrhage causes displacement of brain tissue, but once resorbed, the patient recovers with fewer deficits compared to similar-sized infarcts. Characteristics of hypertensive hemorrhages that lead to poorer prognosis include :

• bleed in the posterior fossa 
• large amount of mass effect 
• extension into the ventricular system 

Video

Siehe auch:

• Intrazerebrale Blutung
• Ponsblutung
• Einblutung in die Basalganglien
• zerebrale Mikroblutungen
• Arterielle Hypertonie
• Atherosklerose
• Kleinhirnblutung
• zerebrale Mikroangiopathie bei Hypertonus

und weiter:

• intermediary injury