Sarkoidose der Milz

Splenic sarcoidosis is a non-caseating granulomatous involvement of the spleen, that presents with splenomegaly or multiple splenic nodules.

Clinical presentation

Clinical features of splenic sarcoidosis include :

  • pain
  • anemia
  • abdominal pain and discomfort
  • splenic enlargement (is associated with involvement of the lungs and the liver)

Radiographic features

On imaging, splenic sarcoidosis mimics an infectious disease or neoplastic process .


CT scan demonstrates homogeneous splenomegaly or the existence of numerous hypointense nodules, making it difficult to differentiate from metastases in the spleen .

  • T1: splenic lesions usually hypointense when related to the background parenchyma
  • T2: hypointense as compared to normal splenic parenchyma.
  • C+ (Gd):  lesion shows no enhancement

Treatment and prognosis

Corticosteroids have a role in the treatment of sarcoidosis. Endoscopic ultrasound guided biopsy followed by splenectomy is the treatment of choice in cases of non-resolution .

Differential diagnosis

Differentials of splenic sarcoidosis include:

See also

Siehe auch:
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