Kolobom | pacs

Toddler with

small orbits. Axial (above) and coronal (below) CT with contrast of the orbits show bilaterally small orbits containing small optic nerves and small extraocular muscles. There is also bilaterally calcification in the center of the vitreous of the globes and colobomatous cysts inferolaterally within the orbits.The diagnosis was microphthalmia and coloboma.

pediatricimaging.org • CC-by-nc-sa 4.0

Coloboma •

Coloboma - Ganzer Fall bei Radiopaedia

Wang, M. Coloboma. Case study, Radiopaedia.org. (accessed on 01 Nov 2022) https://doi.org/10.53347/rID-13937 • CC by-nc-sa 3.0 (modified)

Coloboma •

Coloboma of optic nerve head - Ganzer Fall bei Radiopaedia

Ibrahim, H. Coloboma of optic nerve head. Case study, Radiopaedia.org. (accessed on 01 Nov 2022) https://doi.org/10.53347/rID-53370 • CC by-nc-sa 3.0 (modified)

Coloboma •

Aicardi syndrome - Ganzer Fall bei Radiopaedia

Haouimi, A. Aicardi syndrome. Case study, Radiopaedia.org. (accessed on 01 Nov 2022) https://doi.org/10.53347/rID-73945 • CC by-nc-sa 3.0 (modified)

Coloboma •

Aicardi syndrome - Ganzer Fall bei Radiopaedia

McEniery, J. Aicardi syndrome. Case study, Radiopaedia.org. (accessed on 01 Nov 2022) https://doi.org/10.53347/rID-66940 • CC by-nc-sa 3.0 (modified)

Coloboma •

Glaucoma and chorioretinal coloboma - Ganzer Fall bei Radiopaedia

Sharifkashani, S. Glaucoma and chorioretinal coloboma. Case study, Radiopaedia.org. (accessed on 01 Nov 2022) https://doi.org/10.53347/rID-146617 • CC by-nc-sa 3.0 (modified)

Morning glory

syndrome (eye) • Morning glory syndrome - Ganzer Fall bei Radiopaedia

Gaillard, F. Morning glory syndrome. Case study, Radiopaedia.org. (accessed on 23 Oct 2022) https://doi.org/10.53347/rID-8236 • CC by-nc-sa 3.0 (modified)

Vitreous

hemorrhage • Coloboma with vitreous hemorrhage - Ganzer Fall bei Radiopaedia

Haouimi, A. Coloboma with vitreous hemorrhage. Case study, Radiopaedia.org. (accessed on 20 Oct 2022) https://doi.org/10.53347/rID-83968 • CC by-nc-sa 3.0 (modified)

Hier werden Begriffe / Krankheitsbilder genannt, die ähnlich sind oder klingen, aber nicht das Gleiche sind.

nicht verwechseln mit: Staphylom

Radiopaedia • CC-by-nc-sa 3.0 • de

Coloboma is a collective term encompassing any focal discontinuity in the structure of the eye, and should not be confused with staphylomas, which are due to choroidal thinning.

Pathology

Embryologically, colobomas are due to the failure of closure of the choroidal fissure. The most common site of ocular coloboma is the anterior segment involving the iris, less commonly in the posterior segment involving the optic disc, choroid, or retina . Coloboma can also involve the eyelids, lens, and optic nerve.

Typically colobomas are bilateral, small and are not accompanied by other deeper abnormalities.

Associations

Variants

morning glory syndrome: optic nerve head coloboma with associated midline structural abnormalities of the brain and skull
coloboma with a cyst (microphthalmia with cyst): results from the proliferation of the embryonic retina with potential extrusion of the vitreous posteriorly into the cyst (thus microphthalmia). The cyst may become discontinuous from the eye, be larger than the eye, and may cause proptosis

Radiographic features

In posterior ocular coloboma, on CT or MRI, the affected globe is usually small with a focal posterior defect in the globe with vitreous herniation . A retrobulbar fluid-density cyst may be present .