The Potter sequence is a constellation of findings demonstrated postnatally as a consequence of severe, prolonged oligohydramnios in utero.

Clinical presentation

It consists of:

These common clinical features can be easily recalled using the mnemonic POTTER.


Although originally associated with renal causes of olighydramnios, the Potter sequence may be seen with severe oligohydramnios of essentially any cause.

Common etiologies include:

Treatment and prognosis

The prognosis is poor with a very high mortality rate, primarily secondary to pulmonary hypoplasia.

History and etymology

It is named after Edith Louise Potter (1901-1993), an American pathologist who described the syndrome specifically in association with bilateral renal agenesis .

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