Expansile lytic lesions without cortical destruction of bone (differential)

Expansile lytic bone lesions without cortical destruction can result from various benign and malignant neoplastic pathologies, causes include :

• unicameral bone cyst
• aneurysmal bone cyst (eccentric)
• enchondroma
• chondromyxoid fibroma (eccentric)
• non-ossifying fibroma (eccentric)
• desmoplastic fibroma
• osteoblastoma
• giant cell tumor (eccentric)
• fibrosarcoma
• chondrosarcoma
• eosinophilic granuloma
• Brown tumor
• haemophilic pseudotumor
• healing or healed fractures
• spina ventosa
• fibrous dysplasia
• intraosseous lipoma