Renal medullary nephrocalcinosis is the commonest form of nephrocalcinosis and refers to the deposition of calcium salts in the medulla of the kidney. Due to the concentrating effects of the loops of Henle, and the biochemical milieu of the medulla, compared to the cortex, it is 20 times more common than cortical nephrocalcinosis.
Often (and perhaps unsurprisingly) the same entities may also lead to nephrolithiasis (renal calculi).
Causes include :
- renal papillary necrosis
- primärer Hyperparathyreoidismus
- Multiples Myelom
- medullary sponge kidney
- Morbus Cushing
- kortikale Nephrokalzinose