WHO classification of tumours of bone
The World Health Organisation (WHO) classification of bone tumours is the most widely used pathologic classification system for such disorders. The current revision, part of the 4 edition of the WHO series, was published in 2013 and is reflected in the article below .
Classification
Chondrogenic tumours
- osteochondroma
- chondromas
- chondromyxoid fibroma
- osteochondromyxoma
- subungual exostosis and bizarre parosteal osteochondromatous proliferation
- synovial chondromatosis
- chondroblastoma
- chondrosarcoma (grades I-III) including primary and secondary variants and periosteal chondrosarcoma
- dedifferentiated chondrosarcoma
- mesenchymal chondrosarcoma
- clear cell chondrosarcoma
Osteogenic tumours
- osteoma
- osteoid osteoma
- osteoblastoma
- low-grade central osteosarcoma
- conventional osteosarcoma
- telangiectatic osteosarcoma
- small cell osteosarcoma
- parosteal osteosarcoma
- periosteal osteosarcoma
- high-grade surface osteosarcoma
Fibrogenic tumours
Fibrohistiocytic tumours
Ewing sarcoma
Haematopoietic neoplasms
- plasma cell myeloma
- solitary plasmacytoma of bone
- primary non-Hodgkin lymphoma of bone
Osteoclastic giant cell-rich tumours
- giant cell lesion of the small bones
- giant cell tumour of bone
Notochordal tumours
- benign notochordal cell tumour
- chordoma
Vascular tumours
- haemangioma
- epithelioid haemangioma
- epithelioid haemangioendothelioma
- angiosarcoma
Myogenic, lipogenic, and epithelial tumours
Tumours of undefined neoplastic nature
- aneurysmal bone cyst
- simple bone cyst
- fibrous dysplasia
- osteofibrous dysplasia
- Langerhans cell histiocytosis
- Erdheim-Chester disease
- chondromesenchymal hamartoma
- Rosai-Dorfman disease
Undifferentiated high-grade pleomorphic sarcoma
- undifferentiated high-grade pleomorphic sarcoma
See also
- WHO classification of tumours of soft tissue
