Tuberkulose
Tuberculosis (commonly abbreviated to TB, short for tubercle bacillus) encompasses an enormously wide disease spectrum affecting multiple organs and body systems predominantly caused by the organism Mycobacterium tuberculosis. A small proportion can also be caused by Mycobacterium bovis.
Epidemiology
Although tuberculosis continues to be very common in developing nations. Approximately 10 million people globally per year have positive exposure to tuberculosis . In Western industrialised populations it has become uncommon but is increasing in prevalence among immunocompromised patients, particularly those with HIV/AIDS. An estimated 5% HIV patients have Mycobacterium tuberculosis infections, which become clinically apparent when CD4+ counts drop to below 350 cells/mm, typically with findings of post-primary pulmonary tuberculosis .
Clinical presentation
Clinical presentation will depend upon the morphology of infection and location. These are discussed in separate articles.
- morphology
- location
History and etymology
Aristotle is usually credited as being the first to recognize the contagious nature of the disease. Discovery of the specific infectious agent, the tubercle bacillus (Mycobacterium tuberculosis), did not occur for several millennia until it was isolated by Robert Koch in 1882 . M. tuberculosis was previously known as Koch bacillus and tuberculosis known as Koch disease. It was also historically known as consumption due to the severe associated weight loss.
Siehe auch:
- pulmonale Tuberkulose
- Pleuraplaques
- Miliartuberkulose
- Tuberkulose des ZNS
- Nierentuberkulose
- miliare Lungenherde
- pleurale Tuberkulose
- Kavernöse Lungenläsionen
- mycobacterium tuberculosis
- primary pulmonary tuberculosis
- tuberkulöse Spondylitis
- Tuberkulose des Peritoneums
- tuberkulöse Halslymphknoten
- urogenitale Tuberkulose
- post primary pulmonary tuberculosis
- Pleuritis exsudativa
- multiresistente Tuberkulose
- post-primary pulmonary tuberculosis
- Tuberkulose der Mamma
- tuberkulöse Meningitis
- pelvine Tuberkulose
- Tuberkulostatikum
- tuberkulöse Otomastoiditis
und weiter:
- Pleurakuppenschwielen
- verkalkte mediastinale Lymphknoten
- Dünndarmileus
- Tumoren der Hypophysenregion
- umgekehrtes Halozeichen Lunge
- Splenomegalie
- Skoliose
- apikale Pleurakappe
- Chylothorax
- reverse halo sign
- pulmonale und mediastinale Sarcoidose
- Amyloidose
- arteriovenöse Malformationen der Lunge
- Fibrothorax
- mediastinal lymphoma
- linitis plastica
- testicular epidermoid
- bilaterale hiläre Lymphadenopathie
- Gibbus
- bilaterale axilläre Lymphadenopathie
- Tuberkulose der Milz
- radiation-induced pulmonary fibrosis
- einzelne Pleuraraumforderung
- retikuläres Muster
- Plombage
- hyperdenser Lymphknoten
- Erythema nodosum
- Anthrakose
- differential diagnosis of calcified pulmonary densities
- renal papillary necrosis (mnemonic)
- Raumforderungen der Trachea
- Nebennierenläsionen
- diffuse Trachealwandverdickung
- tuberculous empyema
- differential of chronic alveolar opacities
- Gynäkomastie
- chronic bilateral airspace opacification
- zentrilobuläre Lungennoduli
- differential diagnosis of unilateral axillary lymphadenopathy
- Vergrößerung der zervikalen Lymphknoten
- Hughes-Stovin-Syndrom
- Skrofeln
- hypertrophic olivary degeneration
- melioidosis
- CNS manifestations of AIDS
- thorakale Plombage
- beschleunigte Skelettreifung
- pulmonary upper zone involvement (mnemonic)
- Thorakoplastik
- bladder calcification (mnemonic)
- papillary necrosis (mnemonic)
- opportunistische Infektionen
- crazy paving-Muster
- Nasenseptumdefekt
- dens erosion
- generalised increased liver echogenicity
- hyperechoic liver
- cystic cervical mass adjacent to the angle of mandible
- Tuberkulose des Larynx
- solitary sclerotic bone lesion with a lucent centre
- Ranke complex
- galaxy sign
- small bowel folds (differential diagnoses)
- Tuberkulose von Leber und Milz
- extrapulmonale Manifestationen der Tuberkulose
- multifocal spinal tuberculosis
- diffuse Trachealverengung
- lytic bone lesion surrounded by marked sclerosis (mnemonic)
- pulmonary manifestations of lymphomatoid granulomatosis
- abdominelle und pelvine Verkalkungen
- Knochenläsionen mit Sequester
- Tuberkulose des Ösophagus
- peritoneal tuberculosis following infliximab therapy
- chronic primary adrenal insufficiency
- tubercular esophagocutaneous fistula
- Tuberkulose der Leber
- Vergrößerung der Glandula parotis
- Phemister triad
- Isoniazid
- Tuberkulose der Wirbelsäule und des Spinalkanals
- idiopathische granulomatöse Mastitis
- chronic tuberculosis
- Nachweis Tbc
- MDR Tuberkulose
- tuberculosis in a child
- Assmanninfiltrat
- Handlungsempfehlung für den Umgang mit Patienten mit vermuteter Tuberkulose
- discrete colonic ulceration
- Großgefäßvaskulitis
- tuberkulöse Lymphadenopathie
- Merkspruch Nasenseptumperforation
- triad of Phemister
- gastrointestinale Fistelbildungen
- ileozökale Tuberkulose
- Ursachen für Perfusionsdefekte in der Lungenventilations / -perfusionsszintigraphie